| Characteristic | Details |
|---|---|
| Generic Name | Misoprostol |
| Formulation | Oral Tablet |
| Available Dosage | 200 mcg |
| Mechanism | Prostaglandin Analog |
| Indications | Ulcer Prevention, Medical Termination |
| Link | Explore More |
Pharmacokinetics
Generic Cytotec 200 mcg operates as a prostaglandin analog. It rapidly transforms post-ingestion. Upon oral administration, the bioavailability is substantial. Misoprostol acid, its active metabolite, attains peak plasma concentrations within 30 minutes. The half-life remains brief, facilitating its rapid action. Metabolism occurs extensively in the liver, with renal excretion managing elimination. No substantial accumulation is noted with recommended dosages.
The pharmacokinetic profile aligns with its therapeutic goals. Efficient absorption ensures prompt action. The drug’s lipophilicity aids in gastrointestinal efficacy. Age, hepatic, and renal impairments could alter pharmacokinetics. Adjustments might be necessary for compromised patients.
Mechanism of Action
Misoprostol, the active constituent, mimics endogenous prostaglandins. Its primary action revolves around gastric mucosa protection. It inhibits gastric acid secretion. Simultaneously, it augments bicarbonate and mucous production. This creates a defensive barrier.
Beyond ulcer prevention, it induces uterine contractions. The action on uterine smooth muscle supports medical pregnancy termination. The dual mechanism underscores its therapeutic versatility. Its binding affinity to specific receptors drives both effects.
FDA-Approved Indications
Generic Cytotec 200 mcg bears several approved indications. Its primary use targets NSAID-induced gastric ulcers. This reflects its gastroprotective properties. Misoprostol is also sanctioned for cervical ripening and labor induction.
Medical termination of pregnancy remains another vital indication. It’s employed in conjunction with mifepristone. This dual-drug regimen ensures efficacy. Healthcare providers must adhere to regulatory guidelines. Off-label uses exist but require expert discretion.
Cautions with Other Medicines
Concomitant use of certain medications demands caution. Antacids containing magnesium elevate diarrhea risk. Patients should avoid such combinations. Mifepristone co-administration follows specific protocols. It’s crucial for medical terminations.
Drug interactions might alter efficacy. Hypotensive drugs could interact due to prostaglandin activity. Caution with antihypertensive agents is advisable. Ensure healthcare professionals assess all concurrent medications.
Toxicity
Toxicity parameters remain clinically significant. Overdose can induce excessive uterine contractions. This poses risks in pregnancy. Gastrointestinal symptoms like diarrhea or abdominal pain may arise.
Serious complications include uterine rupture in susceptible patients. Dose adjustments mitigate risk. Vigilance in patient monitoring enhances safety. For more comprehensive safety details, refer to the National Library of Medicine.
Is Non-Prescription Generic Cytotec Available?
Generic Cytotec 200 mcg is primarily prescription-based. Regulatory bodies enforce this due to potential misuse. Over-the-counter availability does not exist. Its use demands medical supervision.
Online sources might claim availability. Such offerings often lack regulatory endorsement. Adhering to prescription guidelines remains paramount. Consultation with healthcare professionals ensures appropriate usage. Proper channels ensure patient safety and therapeutic efficacy.
| Aspect | Details |
|---|---|
| Dosage Form | Tablet |
| Strength | 200 mcg |
| Primary Function | Gastroprotection, Uterotonic |
